Emotion regulation (ER) is the ability to alter the emotional impact of a stimulus or situation. Although the neural underpinnings of ER have been investigated in numerous fMRI studies, the stability and reliability of the underlying networks remains unknown.
In this study we tested the reliability of resting-state fMRI functional connectivity in four networks of emotion generation and regulation identified in a recent meta-analytic study.
Meta-analytic brain networks of emotion regulation
Recent models suggest that cognitive emotion regulation is based upon neural systems implicated in generation and regulation of emotional responses as well as systems with an undefined or intermediary role.
We applied meta-analytic clustering of emotion regulation studies to:
group emotion regulation studies based on similar brain activation patterns
characterize the cognitive and affective processes associated with each of the resulting networks
Are amygdala and PFC connected during emotion regulation?
Single studies usually provide limited insight into the function of specific brain regions.
Thus, to better understand the role of the amygdala in emotion regulation, we performed coordinate-based meta-analysis on studies of emotion regulation related connectivity of the amygdala which used functional magnetic resonance imaging (fMRI) and psychophysiological interaction (PPI) analysis.